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曾志荣

中山大学附属第一医院消化内科教授、博士生导师,科主任。

一、学术兼职

(1)广东省医学会消化病学分会常委,兼炎症性肠病学组组长;

(2)中华消化病学分会幽门螺杆菌学组副组长。

二、研究方向及科研基金

研究方向:(1)幽门螺杆菌相关性疾病;(2)胃癌遗传易感性研究;(3)炎症性肠病流行病学及遗传易感性研究。目前主持国家自然基金一项,广东省自然科学基金一项。

三、成果奖励

2011年成果”胃癌遗传、发病机制及化学预防研究”获广东省然科学奖二等奖(项目负责人)

 

 

科研论文(SCI收录论文)

1. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China.Gut. 2003 Dec;52(12):1684-9.(第1作者)PMID: 14633943

2. Incidence and clinical characteristics of Inflammatory Bowel Disease in a developed region of Guangdong province, China: A Prospective Population-Based Study.J GastroenterolHepatol. 2013 Feb 22.(第1作者)

3. Polymorphisms in prostate stem cell antigen gene rs2294008 increase gastric cancer risk in Chinese.MolCarcinog. 2011 May;50(5):353-8. (第1作者、通讯作者)PMID: 21268123

4. IL23R +2199A/C polymorphism is associated with decreased risk of certain subtypes of gastric cancer in Chinese: a case-control study.Cancer Epidemiol. 2011 Apr;35(2):165-9. (通讯作者)PMID: 20863779

5. Association between the TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms and gastric cancer: a case-control study. OncolLett. 2011 Mar;2(2):371-377. (通讯作者)PMID: 22866090

6. Association between polymorphisms in interleukin-17A and interleukin-17F genes and risks of gastric cancer. Int J Cancer. 2010 Jul 1;127(1):86-92.(通讯作者) PMID: 19904747

7. IL-1B-511 polymorphism is associated with increased risk of certain subtypes of gastric cancer in Chinese: a case-control study.Am J Gastroenterol. 2010 Mar;105(3):557-64. (共同第1作者)PMID: 19904240

8. Contribution of rs11465788 in IL23R gene to Crohn's disease susceptibility and phenotype in Chinese population. J Genet. 2009 Aug;88(2):191-6.(通讯作者) PMID: 19700857

9. Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population. Scand J Gastroenterol. 2009;44(6):720-6.(通讯作者)PMID: 19263269

10. Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway. Cancer Lett. 2007 Jun 28;251(2):268-77. (共同第1作者)PMID: 17257745

11. Peroxisome proliferator-activated receptor-gamma Pro12Ala polymorphism, Helicobacter pylori infection and non-cardia gastric carcinoma in Chinese. Aliment PharmacolTher. 2006 Jan 15;23(2):289-94.(第2作者)PMID: 16393309

12. Xu-Yong Sun, Zhi-Rong Zeng, Zhuang Chen, Jiang Nong, Ke Qin, Hong Lu, Garth L. Warnock and Long-Jun Dai. MESENCHYMAL STEM CELLS AND CANCER. In: Mesenchymal Stem Cells. Editor: Yin Xiao. ISBN: 978-1-61324-669-6. 2012 Nova Science Publishers, Inc. p379-402.

13. Potential implications of mesenchymal stem cells in cancer therapy. Cancer Lett. 2011 Jun 1;305(1):8-20. Review.(第3作者) PMID: 21396770

14. IκBα polymorphisms were associated with increased risk of gastric cancer in a southern Chinese population: a case-control study. Life Sci. 2011 Apr 25;88(17-18):792-7. (第3作者)PMID: 21376060

15. IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese. BMC Gastroenterol. 2010 Feb 5;10:15.(第3作者) PMID: 20132559

16. Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression.Oncol Rep. 2008 Nov;20(5):1093-7.(第3作者) PMID: 18949406

17. Chemoprevention of gastric cancer by celecoxib in rats.Gut. 2004 Feb;53(2):195-200.(第3作者)PMID: 14724149

18. Polymorphisms in interleukin-6-6331 influences the susceptibility of a Chinese population to gastric cancer. Cancer Invest. 2011 Oct;29(8):564-72. (第4作者)PMID: 21843047

19. Different cell kinetic changes in rat stomach cancer after treatment with celecoxib or indomethacin: implications on chemoprevention.World J Gastroenterol. 2005 Jan 7;11(1):41-5.(第6作者)PMID: 15609394

20. Blockade of STAT3 by antisense oligonucleotide in TNBS-induced murine colitis.Int J Colorectal Dis. 2007 Jun;22(6):625-35. (第7作者)PMID: 17089128

21. Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival. Gut. 2012 Jul;61(7):977-85. (第8作者)PMID: 21917650

22. Zinc finger E-box binding factor 1 plays a central role in regulating Epstein-Barr virus (EBV) latent-lytic switch and acts as a therapeutic target in EBV-associated gastric cancer. Cancer. 2012 Feb 15;118(4):924-36. (第10作者)PMID: 21717425