东健 （Azuma Takeshi）
现为神户大学大学院医学研究科消化内科教授，主要从事幽门螺杆菌的基础与临床研究。
研究工作经历
1981年 毕业于京都府立医科大学，获医学博士学位
2001年 福井医科大学第二内科，助教
2005年 神户大学医学部附属医学医疗国际交流中心
难治性疾患病态解析分野 教授
神户大学医学部附属医院 消化内科科长
2007年 神户大学大学院医学研究科消化内科 教授
所属学会
日本内科学会、日本消化器病学会、日本消化器内视镜学会、日本消化管学会、日本肝脏学会、日本胃癌学会、日本Helicobacter学会、World Society of Gastroenterology、The American Gastroenterological Association等
幽门螺杆菌相关研究项目
1. 亚洲Helicobacter感染及相关消化疾病预防对策调查研究（2013-2015）
2. 亚洲幽门螺杆菌感染与胃癌预防研究（2011-2015）
3. Helicobacter感染与消化疾病的免疫学调查研究 (2010-2013)
4. 幽门螺杆菌感染后胃癌诱导因子的免疫学解析研究（2008-2011）
主要研究成果
1: Higuchi K, Takeuchi T, Uedo N, Takeuchi Y, Naito Y, Yagi N, Tominaga K,Machida H, Tamada T, Morita Y, Yazumi S, Yamao J, Iguchi M, Azuma T. Efficacy and safety of 1-week Helicobacter pylori eradication therapy and 7-week rebamipide treatment after endoscopic submucosal dissection of early gastric cancer in comparison with 8-week PPI standard treatment: a randomized, controlled, prospective, multicenter study. Gastric Cancer. 2014 Aug 7. [Epub ahead of print]
2: Kawara F, Inoue J, Takenaka M, Hoshi N, Masuda A, Nishiumi S, Kutsumi H, Azuma T, Ohdaira T. The influences of pepsin concentrations and pH levels on the disinfective activity of ozone nanobubble water against helicobacter pylori. Digestion. 2014;90(1):10-7.
3: Iwamoto A, Tanahashi T, Okada R, Yoshida Y, Kikuchi K, Keida Y, Murakami Y,
Yang L, Yamamoto K, Nishiumi S, Yoshida M, Azuma T. Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes. Gut Pathog. 2014 Jun 26;6:27.
4: Yamanouchi J, Azuma T, Yakushijin Y, Hato T, Yasukawa M. Dramatic and prompt efficacy of Helicobacter pylori eradication in the treatment of severe refractory iron deficiency anemia in adults. Ann Hematol. 2014 Oct;93(10):1779-80.
5: Yamada S, Kato S, Matsuhisa T, Makonkawkeyoon L, Yoshida M, Chakrabandhu T, Lertprasertsuk N, Suttharat P, Chakrabandhu B, Nishiumi S, Chongraksut W, Azuma T. Predominant mucosal IL-8 mRNA expression in non-cagA Thais is risk for gastric cancer. World J Gastroenterol. 2013 May 21;19(19):2941-9.
6: Kido M, Watanabe N, Aoki N, Iwamoto S, Nishiura H, Maruoka R, Ikeda A, Azuma T, Chiba T. Dual roles of CagA protein in Helicobacterpylori-induced chronic gastritis in mice. Biochem Biophys Res Commun. 2011 Aug 26;412(2): 266-72.
7: Kawai M, Furuta Y, Yahara K, Tsuru T, Oshima K, Handa N, Takahashi N, Yoshida M, Azuma T, Hattori M, Uchiyama I, Kobayashi I. Evolution in an oncogenic bacterial species with extreme genome plasticity: Helicobacter pylori East Asian genomes. BMC Microbiol. 2011 May 16;11:104.
8: Cortes MC, Yamakawa A, Casingal CR, Fajardo LS, Juan ML, De Guzman BB, Bondoc EM; St. Luke's Helicobacter pylori Study Group, Mahachai V, Yamazaki Y, Yoshida M, Kutsumi H, Natividad FF, Azuma T. Diversity of the cagA gene of Helicobacter pylori strains from patients with gastroduodenal diseases in the Philippines. FEMS Immunol Med Microbiol. 2010 Oct;60(1):90-7.
9: Tanaka H, Yoshida M, Nishiumi S, Ohnishi N, Kobayashi K, Yamamoto K, Fujita T, Hatakeyama M, Azuma T. The CagA protein of Helicobacter pylori suppresses the
functions of dendritic cell in mice. Arch Biochem Biophys. 2010 Jun 1;498(1):35-42.
10: Mizuno S, Miki I, Ishida T, Yoshida M, Onoyama M, Azuma T, Habu Y, Inokuchi H, Ozasa K, Miki K, Watanabe Y. Prescreening of a high-risk group for gastric cancer by serologically determined Helicobacter pylori infection and atrophic gastritis. Dig Dis Sci. 2010 Nov;55(11):3132-7.
11: Hirai I, Sasaki T, Kimoto A, Yamamoto Y, Azuma T, Mahachai V, Hansomburana P, Lertkupinit C, Luangjaru S, Noophan P, Chanatrirattanapan R, Piyanirandr V, Sappajit T, Suthivarakom K, Sangsuk L, Wangroongsarb P. Infection of less virulent Helicobacter pylori strains in asymptomatic healthy individuals in Thailand as a potential contributing factor to the Asian enigma. Microbes Infect. 2010 Mar;12(3):227-30.